| Cat.No. | Name | Information |
|---|---|---|
| M25289 | Girentuximab | Girentuximab (G250) is a chimeric monoclonal antibody that binds carbonic anhydrase IX (CAIX), a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC). |
| M18209 | Dehydrodiconiferyl alcohol | Dehydrodiconiferyl alcohol |
| M8866 | Zonisamide sodium salt | Zonisamide sodium salt is an antiepileptic compound. |
| M5591 | Dorzolamide HCl | Dorzolamide HCl is a water-soluble inhibitor of human carbonic anhydrase carbonic anhydrase II and IV with a Ki of 1.9 nM and 31 nM, respectively, and can be used in glaucoma-related studies. |
| M3856 | Acetazolamide | Acetazolamide is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM. |
| M3421 | Dichlorphenamide | Dichlorphenamide is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class. |
| M3305 | Tioxolone | Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM. |
| M3099 | U-104 | U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II. |
| M2843 | Methyclothiazide | Methyclothiazide (MCTZ) is an orally active, substituted benzothiazide that also antagonizes extracellular voltage-dependent calcium channel (VDCC) activity. It can be used in the study of hypertension-related diseases. |
| M2840 | Methazolamide | Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively. |
| M2709 | Fluorometholone Acetate | Fluorometholone Acetate is a synthetic corticosteroid and a potent carbonic anhydrase (CA) inhibitor with IC50s of 2.18 μM for hCA-I and 17.5 μM for hCA-II. It has anti-inflammatory activity and may be used in studies related to steroid-responsive ocular inflammation. |
| M2690 | Ethoxzolamide | Ethoxzolamide is an inhibitor of the metalloenzyme carbonic anhydrase, which inhibits hCA I, hCA II, hCA IV, hCA VI and hCA VII with Ki of 25 nM, 8 nM, 93 nM, 43 nM and 0.8 nM, respectively. |
| M2469 | Brinzolamide | Brinzolamide (Brinzolamide) is a potent and effective carbonic anhydrase-II inhibitor with an IC50 of 3.19 nM.In addition, Brinzolamide reduces intraocular aqueous humor production in the eye and may be used in studies related to glaucoma. |
| M2444 | Benzthiazide | Benzthiazide is a thiazide diuretic, promoting water loss from the body. |
| M56595 | hCAIX-IN-5 | hCAIX-IN-5 is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively. |
| M56594 | Disulfamide | Disulfamide, an orally active diuretic, is a carbonic anhydrase inhibitor with the IC50 value of 0.07 μM. |
| M56593 | Quinethazone | Quinethazone is an orally active diuretic agent and is also a weak inhibitor of carbonic anhydrase. |
| M49459 | Acetazolamide sodium | Acetazolamide sodium is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX.Acetazolamide reduces the production of intraocular aqueous humor and may be used in glaucoma-related studies. |
| M42299 | WES-1 | WES-1 is an inhibitor of carbonic anhydrase IX (Ki: 55.9 μM). |
| M42298 | CA inhibitor 2 | CA inhibitor 2 is a carbonic anhydrase inhibitor (IC50: 0.033 μM). |
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