Inhibitors
Cat.No. | Name | Information |
---|---|---|
M9685 | cFMS Receptor Inhibitor II | cFMS Receptor Inhibitor II is a CSF1R kinase inhibitor. |
M9512 | PLX5622 | PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor with an Ki of 5.9 nM. |
M5316 | BLZ945 | BLZ945 is an orally active, potent and selective CSF-1R inhibitor with IC50 of 1 nM, >1000-fold selective against its closest receptor tyrosine kinase homologs. |
M2743 | GW2580 | GW2580 is a selective CSF-1R inhibitor for c-FMS with IC50 of 30 nM, 150- to 500-fold selective compared to b-Raf, CDK4, c-KIT, c-SRC, EGFR, ERBB2/4, ERK2, FLT-3, GSK3, ITK, JAK2 etc. |
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