About 2 results found for searched term "1613191-99-3" (0.16 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10852 | M-4344 | Others |
| VX-803 (M4344, ATR inhibitor 2) is a selective inhibitor of ATAxia telangiectasia and Rad3 related (ATR) kinase with a Ki value of less than 150 pM. VX-803 (M4344) effectively inhibits ATR-driven phosphorylated checkpoint kinase-1 (P-Chk1) phosphorylation with an IC50 value of 8 nM. VX-803 (M4344) has potential antitumor activity. | ||
| M11251 | Gartisertib | ATM/ATR |
| VX-803; M4344; ATR inhibitor 2 | ||
| Gartisertib (VX-803) is an ATP-competitive, orally active, selective ATR inhibitor with Ki<150 pM. Gartisertib inhibits atR-driven phosphorylation of checkpoint kinase-1 (Chk1) with an IC50 value of 8 nM. It has antitumor activity. | ||
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