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Triheptanoin

Cat. No. M10068
Triheptanoin Structure
Synonym:

IND106011; UX007

Size Price Availability Quantity
5mg USD 420  USD420 In stock
10mg USD 820  USD820 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Triheptanoin is a fatty acid metabolic modulator. Triheptanoin is potentially used for the treatment of fatty acid oxidation disorders and GLUT1.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 428.61
Formula C24H44O6
CAS Number 620-67-7
Purity >98%
Solubility DMSO
Storage at -20°C
References

[1] Xiaodong Yuan, et al. J Alzheimers Dis. Triheptanoin Mitigates Brain ATP Depletion and Mitochondrial Dysfunction in a Mouse Model of Alzheimer's Disease

[2] Zeinab Wehbe, et al. J Inherit Metab Dis. Therapeutic potential of triheptanoin in metabolic and neurodegenerative diseases

[3] Kah Ni Tan, et al. J Neurochem. Triheptanoin protects against status epilepticus-induced hippocampal mitochondrial dysfunctions, oxidative stress and neuronal degeneration

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Keywords: Triheptanoin, IND106011; UX007 supplier, FAS, inhibitors

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