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Triclosan

Cat. No. M6031
Triclosan Structure
Synonym:

Irgasan, Cloxifenolum

Size Price Availability Quantity
100mg USD 50 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Triclosan is a diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 289.54
Formula C12H7Cl3O2
CAS Number 3380-34-5
Purity >99%
Solubility 57 mg/mL in DMSO
Storage at -20°C
References

Triclosan and prescription antibiotic exposures and enterolactone production in adults.
Adgent MA, et al. Environ Res. 2015 Oct;142:66-71. PMID: 26114916.

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Keywords: Triclosan, Irgasan, Cloxifenolum supplier, inhibitors

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