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TMPH hydrochloride is a potent non-competitive antagonist of neuronal nicotinic ACh receptors (nAChRs). Produces long-lasting inhibition of neuronal nAChRs formed by the combination of the most abundant α and β subunits (i.e. α3, α4 and β2, β4 respectively). Displays little inhibition of muscle-type (α1β1γδ) or α7 receptors.
| Molecular Weight | 305.88 |
| Formula | C16H31NO2.HCl |
| CAS Number | 849461-91-2 |
| Solubility (25°C) | DMSO 30.59 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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