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TC-G 1001 is a gPR35 agonist (pEC50 values are 7.59 and 8.36 for β-arrestin and Gαq-i5 Ca2+ assays respectively). TC-G 1001 displays 1000-fold greater potency at human GPR35 receptors relative to mouse and rat GPR35 orthologs in an IP1 accumulation assay. More potent than zaprinast.
| Molecular Weight | 342.34 |
| Formula | C17H11FN2O3S |
| CAS Number | 494191-73-0 |
| Solubility (25°C) | DMSO 3.42 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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