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TC-E 5006

Cat. No. M7367

All AbMole products are for research use only, cannot be used for human consumption.

TC-E 5006 Structure

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Quality Control & Documentation
Biological Activity

TC-E 5006 is a γ-secretase modulator. Reduces Aβ42 levels in vitro (EC50 = 390 nM) and in vivo. Orally bioavailable.

Chemical Information
Molecular Weight 499.54
Formula C29H29F4NO2
CAS Number 1257395-14-4
Solubility (25°C) DMSO 49.95 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Bai, et al. J Biol Chem. Identification of cysteine 354 of β-tubulin as part of the binding site for the A ring of colchicine.

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Keywords: TC-E 5006 supplier, inhibitors, activators

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