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Spermine NONOate

Cat. No. M7318

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Spermine NONOate Structure
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10mg USD 135  USD135 Out of stock
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Quality Control & Documentation
Biological Activity

Spermine NONOate is a a stable complex of nitric oxide and spermine used to generate a controlled release of nitric oxide in solution (EC50 = 6.2 μM for relaxation of rabbit aorta, and t½ =39 min at 37°C, pH 7.4, aqueous solution).

Chemical Information
Molecular Weight 262.35
Formula C10H26N6O2
CAS Number 136587-13-8
Solubility (25°C) Water 26.23 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Bessho, et al. Biochem Pharmacol. Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor κB (NF-κB) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes.

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