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Sodium L-lactate

Cat. No. M31103
Sodium L-lactate Structure
Synonym:

L-Lactic acid sodium salt

Size Price Availability Quantity
5g USD 160  USD160 In stock
10g USD 220  USD220 In stock
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Quality Control & Documentation
Biological Activity

Sodium L-lactate can be used as a casein toughening agent and water absorbent. sodium L-lactate can inhibit the multiplication of most spoilage bacteria and has different degrees of inhibition on many pathogenic bacteria such as Listeria monocytogenes, Salmonella and Clostridium botulinum. Sodium L-lactate is also used as an antioxidant synergist, emulsifier and humectant.

Chemical Information
Molecular Weight 112.06
Formula C3H5NaO3
CAS Number 867-56-1
Form Powder
Solubility (25°C) Water ~50 mg/mL
Storage 2-8°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] B Hildmann, et al. Biochem J. Sodium ion/L-lactate co-transport in rabbit small-intestinal brush-border-membrane vesicles

[2] C Storelli, et al. Pflugers Arch. Polar distribution of sodium-dependent and sodium-independent transport system for L-lactate in the plasma membrane of rat enterocytes

[3] B Barbarat, et al. J Biol Chem. Stoichiometry of the renal sodium-L-lactate cotransporter

[4] S Wolffram, et al. J Dairy Sci. Sodium-dependent L-lactate uptake by bovine intestinal brush border membrane vesicles

[5] T R Kasari, et al. J Am Vet Med Assoc. Clinical evaluation of sodium bicarbonate, sodium L-lactate, and sodium acetate for the treatment of acidosis in diarrheic calves

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