SNAP 94847 Hydrochloride is a novel high affinity selective melanin concentration hormone receptor 1 (MCHR1) antagonist with antidepressant like activity. SNAP 94847 Hydrochloride is a high-affinity antagonist (pA2=7.81) of MYo-inositol phosphate formation induced by MCH.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
|Solubility||DMSO ≥ 100 mg/mL|
|Storage||4°C , dry , sealed|
Balofloxacin Dihydrate is an agonist of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway
2-Aminoisobutyric acid is a rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin.
Cyclohexanecarboxylic acid is a Valproate structural analogue with anticonvulsant action.
Cefozopran HCl is a fourth-generation cephalosporin.
|Cefotiam Hexetil Hydrochloride
Cefotiam Hexetil Hydrochloride is a semi-synthetic cephalosporin antibiotic, and an antibacterial. the compound has broad spectrum activity against gram-positive and -negative bactera.
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