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Sethoxydim

Cat. No. M42278
Sethoxydim Structure
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Quality Control & Documentation
Biological Activity

Sethoxydim is a postemergent herbicide.

Chemical Information
Molecular Weight 327.48
Formula C17H29NO3S
CAS Number 74051-80-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Tao Song et al. Sci Rep. Transcriptome analysis identified the mechanism of synergy between sethoxydim herbicide and a mycoherbicide on green foxtail

[2] Beatriz Sevilla-Morán et al. Chemosphere. Photodegradation behaviour of sethoxydim and its comercial formulation Poast® under environmentally-relevant conditions in aqueous media. Study of photoproducts and their toxicity

[3] Aicha Belkebir et al. Pestic Biochem Physiol. Sethoxydim treatment inhibits lipid metabolism and enhances the accumulation of anthocyanins in rape (Brassica napus L.) leaves

[4] Aicha Belkebir et al. J Exp Bot. Sethoxydim affects lipid synthesis and acetyl-CoA carboxylase activity in soybean

[5] W B Parker et al. Plant Physiol. Selection and characterization of sethoxydim- tolerant maize tissue cultures

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Keywords: Sethoxydim supplier, Acetyl-CoA Carboxylase, inhibitors, activators


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