Free shipping on all orders over $ 500

Sertraline hydrochloride

Cat. No. M3006

All AbMole products are for research use only, cannot be used for human consumption.

Sertraline hydrochloride Structure
Size Price Availability Quantity
5mg USD 40  USD40 In stock
10mg USD 60  USD60 In stock
25mg USD 90  USD90 In stock
50mg USD 130  USD130 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?
Quality Control & Documentation
Biological Activity

Sertraline hydrochloride is a 5-HT antagonist with Ki of 13 nM.

Product Citations
Protocol (for reference only)
Cell Experiment
Cell lines
Preparation method
Concentrations
Incubation time
Animal Experiment
Animal models Rats, Mice
Formulation In water or the mixture (% by volume), 5% ethanol + 5% Emulphor-EL-620 + 90%normal saline.
Dosages
Administration i.p.
Chemical Information
Molecular Weight 342.69
Formula C17H17Cl2N.HCl
CAS Number 79559-97-0
Form Solid
Solubility (25°C) DMSO 50 mg/mL
Storage 2-8°C
References

[1] Sheila A M Rauch, et al. Efficacy of Prolonged Exposure Therapy, Sertraline Hydrochloride, and Their Combination Among Combat Veterans With Posttraumatic Stress Disorder: A Randomized Clinical Trial

[2] Alessandro Cuomo, et al. Using sertraline in postpartum and breastfeeding: balancing risks and benefits

[3] Andrea Cipriani, et al. Sertraline versus other antidepressive agents for depression

[4] Pediatric OCD Treatment Study (POTS) Team. Cognitive-behavior therapy, sertraline, and their combination for children and adolescents with obsessive-compulsive disorder: the Pediatric OCD Treatment Study (POTS) randomized controlled trial

[5] C Lindsay DeVane, et al. Clinical pharmacokinetics of sertraline

Related 5-HT Receptor Products
Tegaserod

Tegaserod is an orally active serotonin receptor 4 (5-HT4R) agonist and a 5-HT2B receptor antagonist. Tegaserod has pKis of 7.5, 8.4 and 7.0 for human recombinant 5-HT2A, 5-HT2B and 5-HT2C receptors, respectively. Tegaserod causes tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation.

cis-Urocanic acid

cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is also an immune modulator that induces immunosuppression.
5-HT2B antagonist-1

5-HT2B antagonist-1 is an orally active 5-HT2B receptor antagonist with an IC50 value of 33.4 nM.

AS19 

AS19 is a potent, selective 5-HT7 receptor agonist with an IC50 value of 0.83 nM and a Ki of 0.6 nM.
CP94253 

CP94253 is a selective, orally active agonist for serotonin receptor 1B (5-HT1B), through competitive binding with iodocyanopindolol (ICP) to the 5-HT1 receptor.
  Catalog
Abmole Inhibitor Catalog




Keywords: Sertraline hydrochloride supplier, 5-HT Receptor, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
Get to Know Us
Customer Support
Resources
Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.