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SC 66 is a allosteric inhibitor of Akt; interferes with pleckstrin homology domain binding to PIP3 and facilitates Akt ubiquitination. Exhibits anticancer activity in vitro and in vivo.
| Molecular Weight | 276.33 |
| Formula | C18H16N2O |
| CAS Number | 871361-88-5 |
| Solubility (25°C) | DMSO 20.72 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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