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SB 611812 is a urotensin-II (UT) antagonist. Inhibits urotensin-II-induced proliferation of neonatal cardiac fibroblasts. Attenuates cardiac dysfunction in a rat model of coronary artery ligation; decreases cardiomyocyte hypertrophy, ventricular dilatation and cardiac remodeling.
| Molecular Weight | 491.74 |
| Formula | C17H16Cl3F3N2O3S |
| CAS Number | 345892-71-9 |
| Solubility (25°C) | DMSO 4.92 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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