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Salbutamol (Albuterol) hemisulfate is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 µM. The tertiary butyl group in salbutamol (or albuterol) makes it more selective for β2-receptors. The compound is sold as a racemic mixture mainly because the S isomer blocks metabolism pathways while the R isomer shows activity. It exerts anabolic effects through androgen receptor agonistic activity in vitro.
| Molecular Weight | 288.14 |
| Formula | C13H21NO3.1/2(H2SO4) |
| CAS Number | 51022-70-9 |
| Solubility (25°C) | Water 90 mg/mL DMSO 2 mg/mL (Need ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] C E Sottas, et al. Salbutamol has rapid onset pharmacodynamics as a bronchodilator
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