Free shipping on all orders over $ 500

(S)-2-Aminohexanedioic acid

Cat. No. M39567
(S)-2-Aminohexanedioic acid Structure
Size Price Availability Quantity
1g USD 30  USD30 In stock
5g USD 90  USD90 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

(S)-2-Aminohexanedioic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Chemical Information
Molecular Weight 161.16
Formula C6H11NO4
CAS Number 1118-90-7
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Haoli Mao et al. Front Endocrinol (Lausanne). High preoperative blood oxaloacetate and 2-aminoadipic acid levels are associated with postoperative delayed neurocognitive recovery

[2] Roderick C Slieker et al. Nat Commun. Identification of biomarkers for glycaemic deterioration in type 2 diabetes

[3] Shuangyuan Wang et al. Cell Rep Med. Amino acids, microbiota-related metabolites, and the risk of incident diabetes among normoglycemic Chinese adults: Findings from the 4C study

[4] Hongqiao Lin et al. Free Radic Biol Med. Myeloperoxidase-mediated protein lysine oxidation generates 2-aminoadipic acid and lysine nitrile in vivo

[5] H Bräuner-Osborne et al. J Med Chem. A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid

Related Products
PRGL493

PRGL493 is a potent and selective long-chain acyl-CoA synthetase 4 (ACSL4) inhibitor. PRGL493 blocks cell proliferation and tumor growth in both breast and prostate cellular and animal models.

Hercynine

Hercynine is a natural product, found in the fine leaf algae, Schizosaccharomyces cerevisiae and honey bees, and is a precursor of L-(+)-ergothioneine.

C24-Ceramide

C24 Ceramide (Lignoceric ceramide) is a naturally occurring ceramide and an integral part of the sphingomyelin cycle. C24 Ceramide (Lignoceric ceramide) stimulates the proliferation of basophilic erythroblasts, suggesting a possible role in erythrocyte maturation.

RNA-protein crosslinking (sulfhydryl addition) agent

RNA-protein crosslinking (sulfhydryl addition) agent is a thiolating agent that is useful in cross-linking proteins. Thiolan-2-imine hydrochloride is a reagent for the introduction of sulphydryl groups into oligosaccharides derived from asparagine-linked glycans.

Izeltabart

Izeltabart is a high-affinity humanized antibody targeting ADAM9. Izeltabart can be used as ADC Antibody for site-specific conjugation with Maytansinoid-based DM21-C to synthesize IMGC936, an Antibody-drug Conjugate with strong anti-cancer activity. IMGC936 exhibits cytotoxicity against ADAM9-positive human tumor cell lines and potent antitumor activity in xenograft tumor models.

  Catalog
Abmole Inhibitor Catalog




Keywords: (S)-2-Aminohexanedioic acid supplier, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.