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Ro 04-6790

Cat. No. M7203

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Ro 04-6790 Structure

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Quality Control & Documentation
Biological Activity

Ro 04-6790 is a potent and selective 5-HT6 receptor antagonist (pKi values are 7.26 and 7.35 at rat and human 5-HT6 receptors respectively). Displays no affinity at a range of other receptors (IC50 > 10 μM). Induces stretching behavior in rats in vivo.

Chemical Information
Molecular Weight 308.36
Formula C12H16N6O2S
CAS Number 202466-68-0
Solubility (25°C) DMSO 30.84 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Evans, et al. Br J Pharmacol. Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog.

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