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Qstatin

Cat. No. M9721
Qstatin Structure
Synonym:

Q-statin

Size Price Availability
10mg USD 180 4-7 Days
25mg USD 290 4-7 Days
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Qstatin is a selective inhibitor of quorum sensing (QS) in vibrio species. QStatin is also a potent and selective inhibitor of SmcR (V. harveyi LuxR homologue) with EC50 of 208.9 nM.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 293.16
Formula C7H5BrN2O2S2
CAS Number 902688-24-8
Purity >99%
Solubility DMSO ≥ 60 mg/mL
Storage 2-8°C, protect from light, dry, sealed
References

QStatin, a Selective Inhibitor of Quorum Sensing in Vibrio Species
Byoung Sik Kim, et al. mBio. 2018 Jan 30;9(1):e02262-17. PMID: 29382732.

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  Catalog
Abmole Inhibitor Catalog 2017




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