Qstatin is a selective inhibitor of quorum sensing (QS) in vibrio species. QStatin is also a potent and selective inhibitor of SmcR (V. harveyi LuxR homologue) with EC50 of 208.9 nM.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Solubility||DMSO ≥ 60 mg/mL|
|Storage||2-8°C, protect from light, dry, sealed|
QStatin, a Selective Inhibitor of Quorum Sensing in Vibrio Species
Byoung Sik Kim, et al. mBio. 2018 Jan 30;9(1):e02262-17. PMID: 29382732.
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