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Pregnenolone sulfate sodium salt is a highly potent neurosteroid; enhances intracellular Ca2+ upon NMDA receptor-mediated synaptic activity (EC50 = ~2 pM) and potentiates NMDA responses. Activates CREB phosphorylation, augments LTP and cognitive behavior in rat memory models. Also activates TRPM3 channels.
| Molecular Weight | 418.52 |
| Formula | C21H31NaO5S |
| CAS Number | 1852-38-6 |
| Solubility (25°C) | DMSO 41.85 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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