Free shipping on all orders over $ 500

Picroside-II

Cat. No. M4412

All AbMole products are for research use only, cannot be used for human consumption.

Picroside-II Structure
Size Price Availability Quantity
5mg USD 80  USD80 In stock
20mg USD 150  USD150 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Picroside II lutein II is a iridoid compound extracted from Lutein, which has anti-inflammatory and anti-apoptotic effects. Picroside II reduces inflammation in sepsis by inhibiting activation of NLRP3 inflammasome and NF-κB pathway. Picroside II is an antioxidant that reduces ROS production and protects the blood brain barrier (BBB) after injury (CI/R) with neuroprotective effects. Picroside II has antioxidant, anti-inflammatory, immunomodulatory, antiviral and other pharmacological activities.

Chemical Information
Molecular Weight 512.46
Formula C23H28O13
CAS Number 39012-20-9
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage 4°C, protect from light, dry, sealed
References

[1] Hui Li, et al. The Protective Effect of Picroside II on Isoflurane-Induced Neuronal Injury in Rats via Downregulating miR-195

[2] Xuehua Piao, et al. Picroside II Improves Severe Acute Pancreatitis-Induced Hepatocellular Injury in Rats by Affecting JAK2/STAT3 Phosphorylation Signaling

[3] Hiteshi Dhami-Shah, et al. Intervention by picroside II on FFAs induced lipid accumulation and lipotoxicity in HepG2 cells

[4] Xuehua Piao, et al. Picroside II Improves Severe Acute Pancreatitis-Induced Intestinal Barrier Injury by Inactivating Oxidative and Inflammatory TLR4-Dependent PI3K/AKT/NF- κ B Signaling and Improving Gut Microbiota

[5] Tingting Li, et al. Picroside II protects against cholestatic liver injury possibly through activation of farnesoid X receptor

Related NF-κB Products
DCZ5418 

DCZ5418 is an inhibitor of TRIP13.

Ro 106-9920 

Ro 106-9920 is a potent inhibitor of NF-kappaB.

MRS2693 trisodium 

MRS2693 trisodium is a selective P2Y6 agonist with an EC50 value of 0.015 μM.

PTD-p65-P1 Peptide TFA

PTD-p65-P1 Peptide TFA is a potent, selective nuclear transcription factor NF-κB inhibitor and derives from the p65 subunit of NF-κB amino acid residues 271-282, which selectively inhibits NF-κB activation induced by various inflammatory stimulation, down-regulate NF-κB-mediated gene expression and up-regulate apoptosis.

Narlumosbart

Narlumosbart is a human IgG4ҡ monoclonal antibody (mAb) that targets Receptor Activating Factor for Nuclear Factor κB Ligand (RANKL) and can be used in studies related to Giant Cell Tumor of Bone (GCTB).

  Catalog
Abmole Inhibitor Catalog




Keywords: Picroside-II supplier, NF-κB, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.