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PF-06260414

Cat. No. M8108

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PF-06260414 Structure

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Quality Control & Documentation
Biological Activity

PF-06260414 is a nonsteriodal selective androgen receptor modulator (SARM). PF-06260414 is being investigated as a treatment for muscle weakening such as that associated with muscular dystrophy and the sarcopenia associated with natural aging. PF-06260414 has anabolic activity without unwanted androgenic activity on reproductive organs, liver or kidneys.

Chemical Information
Molecular Weight 302.35
Formula C14H14N4O2S
CAS Number 1612755-71-1
Solubility (25°C) DMSO: 5 mg/mL (warmed)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Charlotte Cutler, et al. Identification of equine in vitro metabolites of seven non-steroidal selective androgen receptor modulators for doping control purposes

[2] Emiliano Ventura, et al. Development of a multi-residue high-throughput UHPLC-MS/MS method for routine monitoring of SARM compounds in equine and bovine blood

[3] Emiliano Ventura, et al. Investigation of stability of selective androgen receptor modulators in urine

[4] Mario Thevis, et al. Mass spectrometric studies on selective androgen receptor modulators (SARMs) using electron ionization and electrospray ionization/collision-induced dissociation

[5] Indranil Bhattacharya, et al. Safety, Pharmacokinetic, and Pharmacodynamic Evaluation After Single and Multiple Ascending Doses of a Novel Selective Androgen Receptor Modulator in Healthy Subjects

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Keywords: PF-06260414 supplier, inhibitors, activators

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