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PF-04979064

Cat. No. M8073

All AbMole products are for research use only, cannot be used for human consumption.

PF-04979064 Structure

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Quality Control & Documentation
Biological Activity

PF-04979064 is an orally available, potent and selective PI3K/mTOR dual kinase inhibitor that potently inhibits tumor growth in mouse xenografts.

Chemical Information
Molecular Weight 446.5
Formula C24H26N6O3
CAS Number 1220699-06-8
Solubility (25°C) DMSO: 2 mg/mL (warmed)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Fang Zhang, et al. The PI3K/AKT/mTOR pathway regulates autophagy to induce apoptosis of alveolar epithelial cells in chronic obstructive pulmonary disease caused by PM2.5 particulate matter

[2] Hengmiao Cheng, et al. Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design

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Keywords: PF-04979064 supplier, inhibitors, activators

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