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Parecoxib

Cat. No. M5858
Parecoxib Structure
Synonym:

SC-69124, Valus-P, Vorth-P

Size Price Availability Quantity
25mg USD 80 In stock
50mg USD 130 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Parecoxib is a selective COX2 inhibitor.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 370.42
Formula C19H18N2O4S
CAS Number 198470-84-7
Purity >99%
Solubility 74 mg/mL in DMSO
Storage at -20°C
References

Parecoxib: an enhancer of radiation therapy for colorectal cancer.
Xiong W, et al. Asian Pac J Cancer Prev. 2015;16(2):627-33. PMID: 25684498.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Parecoxib, SC-69124, Valus-P, Vorth-P supplier, COX, inhibitors

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