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Oxcarbazepine

Cat. No. M2264
Oxcarbazepine Structure
Synonym:

Trileptal

Size Price Availability Quantity
10mg USD 72 In stock
50mg USD 215 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Oxcarbazepine is an anticonvulsant and mood-stabilizing compound used primarily in the treatment of epilepsy. Oxcarbazepine protects mice and rats against generalized tonic-clonic seizures induced by electroshock. Oxcarbazepine is also used to treat anxiety and mood disorders, and benign motor tics.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 252.27
Formula C15H12N2O2
CAS Number 28721-07-5
Purity >98%
Solubility DMSO
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Oxcarbazepine, Trileptal supplier, Sodium Channel, inhibitors

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