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Ofloxacin

Cat. No. M5832
Ofloxacin Structure
Synonym:

DL8280

Size Price Availability Quantity
100mg USD 50 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Ofloxacin is a synthetic broad-spectrum antimicrobial agent.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 361.37
Formula C18H20FN3O4
CAS Number 82419-36-1
Purity >99%
Solubility 0.4 mg/mL in DMSO
Storage at -20°C
References

Molecular modeling application on hapten epitope prediction: an enantioselective immunoassay for ofloxacin optical isomers.
Mu H, et al. J Agric Food Chem. 2014 Aug 6;62(31):7804-12. PMID: 25069865.

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  Catalog
Abmole Inhibitor Catalog 2017




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