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(+,-)-Octopamine

Cat. No. M5350
(+,-)-Octopamine  Structure
Size Price Availability Quantity
50mg USD 70 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Octopamine is present in relatively high concentrations in neuronal as well as in non-neuronal tissues of most invertebrate species studied, and modulates almost every physiological process. Octopamine acts as neurohormone including desensitization of sensory inputs, influence on learning and memory, or regulation of the mood of the animal in the central nervous system. Octopamine is the only neuroactive non-peptide transmitter whose physiological role is restricted to invertebrates, and all octopamine receptors belong to the family of G-protein coupled receptors.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 189.64
Formula C8H11NO2.HCl
CAS Number 770-05-8
Purity >99%
Solubility 38 mg/mL in DMSO
Storage at -20°C
References

Octopamine mediates starvation-induced hyperactivity in adult Drosophila.
Yang Z, et al. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5219-24. PMID: 25848004.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: (+,-)-Octopamine supplier, Dopamine Receptor, inhibitors

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