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NSC 624206 is a ubiquitin-activating enzyme (E1) inhibitor; prevents tumour suppressor protein p27 ubiquitination in vitro. Blocks the ubiquitin-thioester formation step of the E1 activation reaction, but displays no effect on ubiquitin adenylation.
| Molecular Weight | 410.51 |
| Formula | C19H32ClNS2.HCl |
| CAS Number | 13116-77-3 |
| Solubility (25°C) | DMSO 20.53 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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