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NP603 is a cell-permeable inhibitor of PDGFRβ, FGFR1 and VEGFR2 that binds to ATP pocket. NP603 is a very weak inhibitor of EGFR (IC50 >100 μM).
| Molecular Weight | 446.5 |
| Formula | C26H26N2O5 |
| CAS Number | 949164-80-1 |
| Solubility (25°C) | DMSO: ≥30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Naparat Kammasud, et al. Novel inhibitor for fibroblast growth factor receptor tyrosine kinase
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