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N-BOC-D-FMK

Cat. No. M9486
N-BOC-D-FMK Structure
Synonym:

Caspase Inhibitor 3

Size Price Availability
5mg USD 144  USD160 4-7 Days
10mg USD 198  USD220 4-7 Days
25mg USD 396  USD440 4-7 Days
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

N-BOC-D-FMK is a Caspase-3 inhibitor.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 263.26
Formula C11H18FNO5
CAS Number 187389-53-3
Purity >98%
Solubility DMSO 10mM
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: N-BOC-D-FMK, Caspase Inhibitor 3 supplier, Caspase, inhibitors

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