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MRS 1220

Cat. No. M6997

All AbMole products are for research use only, cannot be used for human consumption.

MRS 1220 Structure

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Quality Control & Documentation
Biological Activity

MRS 1220 is a a potent and highly selective antagonist at the human A3 adenosine receptor (Ki values are 0.65, 305, and 52 nM at hA3, rA1 and rA2A respectively. Displays an IC50 value > 1 μM for inhibition of binding to rat A3 receptors).

Chemical Information
Molecular Weight 403.83
Formula C21H14ClN5O2
CAS Number 183721-15-5
Solubility (25°C) DMSO 8.08 mg/mL (with gentle warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Boeglin, et al. PLoS One. Toll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cells.

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