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ML264

Cat. No. M8650

All AbMole products are for research use only, cannot be used for human consumption.

ML264 Structure
Synonym:

CID-51003603

Size Price Availability Quantity
10mM*500uL in DMSO USD 49  USD49 In stock
1mg USD 32  USD32 In stock
5mg USD 75  USD75 In stock
10mg USD 110  USD110 In stock
25mg USD 213  USD213 In stock
50mg USD 360  USD360 In stock
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Quality Control & Documentation
Biological Activity

ML264 is a potent and selective inhibitor of Kruppel-like factor 5 (KLF5) expression. ML264 potently inhibits proliferation of colorectal cancer cells in vitro through modifications of the cell-cycle profile.

Chemical Information
Molecular Weight 384.88
Formula C17H21ClN2O4S
CAS Number 1550008-55-3
Solubility (25°C) DMSO ≥ 80 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hai Huang, et al. ML264 inhibits osteosarcoma growth and metastasis via inhibition of JAK2/STAT3 and WNT/β-catenin signalling pathways

[2] Ainara Ruiz de Sabando, et al. ML264, A Novel Small-Molecule Compound That Potently Inhibits Growth of Colorectal Cancer

[3] Agnieszka Bialkowska, et al. ML264: An Antitumor Agent that Potently and Selectively Inhibits Krüppel-like Factor Five (KLF5) Expression: A Probe for Studying Colon Cancer Development and Progression

Related KLF Products
SR18662 

SR18662 is a potent inhibitor of Krüppel-like factor five (KLF5) with an IC50 of 4.4 nM and an analogue of ML264 with improved inhibitory potency against colorectal cancer cells. SR18662 can be used for the study of colorectal cancer.
  Catalog
Abmole Inhibitor Catalog




Keywords: ML264, CID-51003603 supplier, KLF, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
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