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LY 2087101 is a allosteric potentiator of α7, α4β2 and α4β4 nAChRs; displays selectivity against α3β4 nAChRs. Thought to potentiate agonist-evoked α7 responses by binding within the nAChR transmembrane region.
| Molecular Weight | 318.39 |
| Formula | C15H11FN2OS2 |
| CAS Number | 913186-74-0 |
| Solubility (25°C) | DMSO 31.84 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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