Free shipping on all orders over $ 500
Lincomycin hydrochloride is a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis. Lincomycin is an antibiotic used to treat a wide variety of bacterial infections. It has been structurally modified by thionyl chloride to its more commonly known 7-chloro-7-deoxy derivative, clindamycin.
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Molecular Weight | 443 |
| Formula | C18H34N2O6S.HCl |
| CAS Number | 859-18-7 |
| Purity | >98% |
| Solubility | DMSO 80 mg/mL |
| Storage | at -20°C |
[1] Bo Cheng, et al. Effects of lincomycin hydrochloride on the neurotoxicity of zebrafish
[3] A M GEDDES, et al. LINCOMYCIN HYDROCHLORIDE: CLINICAL AND LABORATORY STUDIES
| Related Antibiotic Products |
|---|
| Olanexidine
Olanexidine is an antiseptic/disinfectant compound with potent bactericidal activity against Gram-negative and Gram-positive bacteria. |
| DIMBOA
DIMBOA is a powerful antibiotic present in maize, wheat, and related grasses, possess growth inhibitory properties against many strains of studied bacteria and fungi, such as Staphylococcus aureus, Escherichia coli as well as against Saccharomyces cerevisiae. |
| Ciprofloxacin hydrochloride
Ciprofloxacin hydrochloride is a β-diketone antibiotic with a broad spectrum antibacterial activity. |
| Tosufloxacin tosylate hydrate
Tosufloxacin tosylate hydrate is a fluoroquinolone antibacterial agent used to treat susceptible infections. |
| Tylosin
Tylosin is a macrolide antibiotic obtained from cultures of Streptomyces fradiae. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.
