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Lansoprazole

Cat. No. M5728

Lansoprazole Structure

Synonym: A-65006, AG-1749

Size Price Availability Quantity
1g USD 60 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Lansoprazole is a proton-pump inhibitor (PPI) which prevents the stomach from producing gastric acid.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 369.36
Formula C16H14F3N3O2S
CAS Number 103577-45-3
Purity >99%
Solubility 74 mg/mL in DMSO
Storage at -20°C
References

Lansoprazole Is Associated with Worsening Asthma Control in Children with the CYP2C19 Poor Metabolizer Phenotype.
Lang JE, et al. Ann Am Thorac Soc. 2015 Jun;12(6):878-85. PMID: 25844821.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Lansoprazole, A-65006, AG-1749 supplier, Potassium Channel, inhibitors

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