Free shipping on all orders over $ 500

L-Phenylalanine

Cat. No. M5756
L-Phenylalanine Structure
Size Price Availability Quantity
1g USD 50 In stock
Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

L-Phenylalanine is an antagonist at α2δ calcium channels with a Ki of 980 nM.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 165.19
Formula C9H11NO2
CAS Number 63-91-2
Purity >99%
Solubility 46 mg/mL in water
Storage at -20°C
References

Therapeutic implication of L-phenylalanine aggregation mechanism and its modulation by D-phenylalanine in phenylketonuria.
Singh V, et al. Sci Rep. 2014 Jan 27;4:3875. PMID: 24464217.

Related Calcium Channel Products
Mirogabalin

Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the CNS.

Ranolazine

Ranolazine is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina.

Levosimendan

Levosimendan is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC), provides treatment for heart failure.

Lercanidipine

Lercanidipine hydrochloride is a calcium channel blocker of the dihydropyridine class.

Lacidipine

Lacidipine is a L-type calcium channel blocker, used for treating high blood pressure.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: L-Phenylalanine supplier, Calcium Channel, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2017 AbMole BioScience. All Rights Reserved.