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KY-05009

Cat. No. M8556

All AbMole products are for research use only, cannot be used for human consumption.

KY-05009 Structure

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Quality Control & Documentation
Biological Activity

KY-05009 is a Traf2- and Nck-interacting kinase (TNIK) inhibitor that inhibits the epithelial-to-mesenchymal transition (EMT) in cancer cells.

Chemical Information
Molecular Weight 352.41
Formula C18H16N4O2S
CAS Number 1228280-29-2
Solubility (25°C) DMSO: 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yura Lee, et al. Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells

[2] Jiyeon Kim, et al. A novel aminothiazole KY-05009 with potential to inhibit Traf2- and Nck-interacting kinase (TNIK) attenuates TGF-β1-mediated epithelial-to-mesenchymal transition in human lung adenocarcinoma A549 cells

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Keywords: KY-05009 supplier, inhibitors, activators

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