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Ketotifen Fumarate

Cat. No. M5722
Ketotifen Fumarate Structure
Size Price Availability Quantity
100mg USD 75 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Ketotifen Fumarate is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 425.5
Formula C19H19NOS.C4H4O4
CAS Number 34580-14-8
Purity >99%
Solubility 8 mg/mL in DMSO
Storage at -20°C
References

Comparison of preservative-free ketotifen fumarate and preserved olopatadine hydrochloride eye drops in the treatment of moderate to severe seasonal allergic conjunctivitis.
Mortemousque B, et al. J Fr Ophtalmol. 2014 Jan;37(1):1-8. PMID: 24388379.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Ketotifen Fumarate supplier, Histamine Receptor, inhibitors

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