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JM6 is a prodrug inhibitor of Kynurenine 3-monooxygenase (KMO) that increases kynurenine acid levels and reduces extracellular glutamate in the brain. JM6 prevents spatial memory deficits, anxiety-related behaviors, and synaptic deletions in mouse models of Alzheimer's disease.
| Molecular Weight | 518.61 |
| Formula | C23H26N4O6S2 |
| CAS Number | 1008119-83-2 |
| Solubility (25°C) | DMSO: 2 mg/mL (warmed) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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