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Isorhoifolin

Cat. No. M16738
Isorhoifolin Structure
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Biological Activity

Isorhoifolin

Chemical Information
CAS Number 552-57-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] N Zaheer Ahmed, et al. J Complement Integr Med. Arq Ajīb - a wonder Unani formulation for inhibiting SARS-CoV-2 spike glycoprotein and main protease - an in silico approach

[2] Osvaldo Yaez, et al. Biomed Pharmacother. Theobroma cacao L. compounds: Theoretical study and molecular modeling as inhibitors of main SARS-CoV-2 protease

[3] Olubukola T Adenubi, et al. Exp Appl Acarol. Isolation and characterization of two acaricidal compounds from Calpurnia aurea subsp. aurea (Fabaceae) leaf extract

[4] A O Ogundaini, et al. Planta Med. Isorhoifolin, a Flavonoid Glycoside from Periploca nigrescens Leaves

[5] Zbigniew Sroka, et al. Z Naturforsch C J Biosci. Antiradical and anti-H2O2 properties of polyphenolic compounds from an aqueous peppermint extract

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