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IP7e is a potent Nurr1 activator (EC50 = 3.9 nM). Delays onset and reduces severity of symptoms in mice with experimental autoimmune encephalomyelitis (EAE). Also suppresses NF-κB signaling. Brain penetrant and orally bioavailable.
| Molecular Weight | 390.43 |
| Formula | C23H22N2O4 |
| CAS Number | 500164-74-9 |
| Solubility (25°C) | DMSO 39.04 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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