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IACS-10759

Cat. No. M9412

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IACS-10759 Structure
Size Price Availability Quantity
1mg USD 65  USD65 In stock
5mg USD 125  USD125 In stock
10mg USD 210  USD210 In stock
25mg USD 420  USD420 In stock
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Quality Control & Documentation
Biological Activity

IACS-10759 is a potent inhibitor of complex I of oxidative phosphorylation (OXPHOS). IACS-10759 is orally bioavailable with excellent physicochemical properties in preclinical species and achieves significant in vivo efficacy with daily oral dosing of 10-25 mg/kg.

Chemical Information
Molecular Weight 562.56
Formula C25H25F3N6O4S
CAS Number 1570496-34-2
Solubility (25°C) DMSO ≥ 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Marina P, et al. AACR; Cancer Res. IACS-10759: A novel OXPHOS inhibitor which selectively kill tumors with metabolic vulnerabilities

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Keywords: IACS-10759 supplier, inhibitors, activators

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