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Hydroxyprogesterone caproate

Cat. No. M5698

Hydroxyprogesterone caproate Structure

Synonym: 17α-Hydroxyprogesterone hexanoate, 17α-Hydroxyprogesterone caproate

Size Price Availability Quantity
100mg USD 60 In stock
500mg USD 180 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Hydroxyprogesterone Caproate is a synthetic progestational agent. It binds to and activates nuclear progesterone receptors in the reproductive system and inhibits ovulation and an alteration in the cervical mucus and endometrium.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 428.60
Formula C27H40O4
CAS Number 630-56-8
Purity >99%
Solubility 85 mg/mL in DMSO
Storage at -20°C
References

Association of 17α-Hydroxyprogesterone Caproate and Risk of Infection.
Mainiero AD, et al. Obstet Gynecol. 2015 Jul;126(1):103-8. PMID: 26241262.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Hydroxyprogesterone caproate, 17α-Hydroxyprogesterone hexanoate, 17α-Hydroxyprogesterone caproate supplier, Estrogen Receptor, inhibitors

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