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Hispanone

Cat. No. M16534
Hispanone Structure
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Biological Activity

Hispanone

Chemical Information
CAS Number 82462-67-7
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Norma G Cuellar. Hisp Health Care Int. Education Is Power

[2] Pilar Ortega. Acad Med. In Reply to Schmuter

[3] Elizabeth A Fitzgerald. J Transcult Nurs. Miracles

[4] Renato D Alarcn, et al. Lancet Psychiatry. Hispanic immigrants in the USA: social and mental health perspectives

[5] G Morgan. J Ethnopharmacol. Hispano-Indian trade of an Indian ceremonial plant, peyote (Lophophohora williamsii), on the Mustang Plains of Texas

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