Heptanoate sodium is an organic sodium salt compound widely used in various industries and laboratories. It can be used as surfactant, emulsifier, lubricant and preservative, etc., and plays an important role in some electronic devices.
Molecular Weight | 152.17 |
Formula | C7H13NaO2 |
CAS Number | 10051-45-3 |
Form | Solid |
Storage | 4°C, dry, sealed |
Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
[4] M Bayés et al. Methods Find Exp Clin Pharmacol. Gateways to Clinical Trials
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