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GR 144053 trihydrochloride

Cat. No. M6762

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GR 144053 trihydrochloride Structure

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Quality Control & Documentation
Biological Activity

GR 144053 trihydrochloride is a a potent and selective platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist (IC50 = 37 nM). Orally active and highly effective at inhibiting thrombus formation in vivo.

Chemical Information
Molecular Weight 454.83
Formula C18H27N5O2.3HCl
CAS Number 1215333-48-4
Solubility (25°C) Water 45.48 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Rosenkilde, et al. J Biol Chem. Molecular mechanism of action of monocyclam versus bicyclam non-peptide antagonists of the CXCR4 chemokine receptor.

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