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Fluvoxamine maleate

Cat. No. M5660
Fluvoxamine maleate Structure
Synonym:

MK-264

Size Price Availability Quantity
50mg USD 96 In stock
100mg USD 120 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Fluvoxamine Maleate is a selective serotonin (5-HT) reuptake inhibitor (SSRI), used in the treatment of obsessive-compulsive disorder.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 434.41
Formula C14H18F3N2O2.C4H4O4
CAS Number 61718-82-9
Purity >99%
Solubility 87 mg/mL in DMSO
Storage at -20°C
References

Sensitive and selective determination of fluvoxamine maleate using a sensitive chemiluminescence system based on the alkaline permanganate-Rhodamine B-gold nanoparticles reaction.
Hassanzadeh J, et al. Luminescence. 2015 Jun;30(4):439-43. PMID: 25214010.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Fluvoxamine maleate, MK-264 supplier, 5-HT Receptor, inhibitors

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