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FH1

Cat. No. M2700

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FH1 Structure
Synonym:

NSC 12407; BRD-K4477

Size Price Availability Quantity
10mM*1mL in DMSO USD 54  USD54 In stock
5mg USD 30  USD30 In stock
10mg USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

FH1 (BRD-K4477) is a small molecule, which promotes differentiation of iPS-derived hepatocytes. FH1 (NSC 12407) enhances hepatocyte functions, and promotes the differentiation of induced pluripotent stem (iPS)-derived hepatocytes toward a phenotype more mature and the maturation of well-differentiated cultures of hepatocyte-like cells (iHeps).

Product Citations
Chemical Information
Molecular Weight 282.34
Formula C17H18N2O2
CAS Number 2719-05-3
Solubility (25°C) DMSO 9 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Sang Luo, et al. Functional hit 1 (FH1)-based rapid and efficient generation of functional hepatocytes from human mesenchymal stem cells: a novel strategy for hepatic differentiation

[2] Petra Cifrov, et al. Division of Labor Between Two Actin Nucleators-the Formin FH1 and the ARP2/3 Complex-in Arabidopsis Epidermal Cell Morphogenesis

[3] Michael D Powell, et al. IL-12 signaling drives the differentiation and function of a T H 1-derived T FH1-like cell population

[4] Denisa Oulehlov, et al. Arabidopsis Class I Formin FH1 Relocates between Membrane Compartments during Root Cell Ontogeny and Associates with Plasmodesmata

[5] Amparo Rosero, et al. Arabidopsis FH1 Formin Affects Cotyledon Pavement Cell Shape by Modulating Cytoskeleton Dynamics

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Keywords: FH1, NSC 12407; BRD-K4477 supplier, inhibitors, activators

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