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Fenoldopam mesylate

Cat. No. M5642
Fenoldopam mesylate Structure
Synonym:

KF 82526 (mesylate), Fenoldopam methanesulfonate, Corlopam mesylate

Size Price Availability Quantity
10mg USD 80 In stock
50mg USD 180 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Fenoldopam is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 401.86
Formula C16H16ClNO3.CH4O3S
CAS Number 67227-57-0
Purity >99%
Solubility 80 mg/mL in DMSO
Storage at -20°C
References

Beneficial effect of fenoldopam mesylate in preventing peak blood lactate level during cardiopulmonary bypass for paediatric cardiac surgery.
Ressia L, et al. Interact Cardiovasc Thorac Surg. 2014 Aug;19(2):178-82. PMID: 24771205.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Fenoldopam mesylate, KF 82526 (mesylate), Fenoldopam methanesulfonate, Corlopam mesylate supplier, Dopamine Receptor, inhibitors

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