Eugenin
CAS Number | 480-34-2 |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
[1] Marcela Barbern, et al. Rev Med Chil. [An update on parathyroid carcinoma]
[3] David Ajasin, et al. Front Cell Infect Microbiol. HIV-1 Tat: Role in Bystander Toxicity
[4] Rommy von Bernhardi, et al. Adv Exp Med Biol. What Is Neural Plasticity?
[5] Lanbo Shi, et al. Front Immunol. Immunometabolism in Tuberculosis
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